Active ingredients:
Tirzepatide (API) 5mg/1mL
Tadalafil (API) 2.5mg/1mL

Inactive ingredients:
SubMagnaTM HMW, Spearmint/Peppermint flavoring

Dose:
Place 1mL under tongue once daily. Hold under tongue for 5 minutes before swallowing.

Tirzepatide Side Effects
Common side effects reported in patients treated with Tirzepatide include:

• Nausea
• Diarrhea
• Vomiting
• Decreased appetite
• Constipation
• Upper abdominal discomfort
• Abdominal pain

Severe side effects can include:

• Pancreatitis
• Hypoglycemia when used with insulin or other insulin secretagogues
• Allergic reactions, including rash, itching, or difficulty breathing

If you experience any severe side effects, stop taking the medication, call 911, and contact your doctor immediately.

Tirzepatide Important Safety Information

• Tirzepatide delays gastric emptying.
• Avoid coadministration with insulin or other insulin secretagogues, other GLP-1 receptor agonists, and other oral medications.
• Follow the Directions for Use included in the patient education leaflet.
• Consider increased clinical or laboratory monitoring for medications that have a narrow therapeutic index or that require clinical monitoring.

Tirzepatide Disclaimer

• Any patient with significant medical issues should seek the care of a primary care provider or specialist.
• This page does not contain all possible side effects, and others may occur. Check with your physician or other healthcare provider for additional information.
• Please note that this information is not exhaustive. For comprehensive details, consult the prescribing information and your doctor.
• If our medical providers determine that a prescription is not appropriate for you, you will be notified and issued a full refund for all costs paid. Any subscription memberships you selected will also be canceled.

Tadalafil Side Effects
The most common side effects, reported in ≥5% of patients treated with tadalafil are:

• Headache
• Back pain
• Muscle aches
• Flushing
• Nasal congestion
• Indigestion
• Nasal congestion
• Indigestion. 

Severe side effects to Tadalafil can include:

• Priapism (prolonged erection lasting more than 4 hours) 
• Sudden vision loss (including NAION) 
• Sudden hearing loss
• Cardiovascular events (such as heart attack or stroke)
• Severe hypotension

Signs of an allergic reaction are:

• Appearance of a rash
• Hives
• Itching
• Blistered or peeling skin
• Tightness in chest
• Swelling of lips/tongue or throat
• Difficulty swallowing
• Difficulty breathing

If you experience any of these side effects, stop taking the medication, call 911, and contact your doctor immediately.

What Drugs or Supplements Interact with The Active Ingredient?

Tadalafil potentiates hypotensive effects. 

Avoid coadministration of tadalafil with nitrates, guanylate cyclase stimulators, other PDE5 inhibitors, and substantial amounts of alcohol. 

Follow the Directions for Use included in this patient education leaflet. 

Consider increased clinical or laboratory monitoring for medications that affect blood pressure or that require dose adjustments, such as alpha-blockers or potent CYP3A4 inhibitors.

Please stop taking the medication and talk to your doctor if you begin experiencing chest pains or notice sudden changes in your vision.
Please seek immediate care for erections lasting longer than 4 hours.

Tadalafil Important Safety Information

• Do not use it if taking nitrates or participating in the use of “poppers.”

Before Taking Tadalafil Suspension:

• Notify your healthcare provider if you have a personal or family history of non-arteritic anterior ischemic optic neuropathy (NAION), priapism, or conditions that may predispose you to priapism (such as sickle cell anemia, multiple myeloma, or leukemia). Do not take tadalafil if you have any of the conditions previously listed or are using nitrates or guanylate cyclase stimulators (such as riociguat). Do not take this medication if you have, or have recently had a heart attack, stroke, unstable angina, severe liver or kidney disease, or uncontrolled blood pressure without consulting your physician. Tadalafil is not indicated for use in women, including those who are pregnant, planning to become pregnant, or breastfeeding.

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